Research Paper Volume 12, Issue 23 pp 24357—24370

A forced swim-based rat model of premenstrual depression: effects of hormonal changes and drug intervention

class="figure-viewer-img"

Figure 8. 5-hydroxytryptamine (5-HT), norepinephrine (NE), γ-aminobutyric acid (GABA), and allopregnanolone (ALLO) levels in the hippocampus. (A) 5-HT levels in the hippocampus. (B) NE levels in the hippocampus. (C) GABA levels in the hippocampus. (D) ALLO levels in the hippocampus. FLX, fluoxetine. **p<0.01 compared to the control group, ***p<0.001 compared to the control group, ##p<0.01 compared to the model group, ###p<0.001 compared to the model group (n=8 in each group; one-way ANOVA followed by post-hoc Tukey’s multiple comparisons test).