Exosomes derived from BDNF-expressing 293T attenuate ischemic retinal injury <i>in vitro</i> and <i>in vivo</i>

Bojing Yan; Lixin Gao; Yingxiang Huang; Xiaolei Wang; Xuqiang Lang; Fancheng Yan; Bo Meng; Xiaowei Sun; Genlin Li; Yanling Wang

doi:doi:10.18632/aging.202245

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Withdrawal Notice

This paper was originally published in Aging Advance Online Publications on November 29, 2020.

In compliance with Aging's withdrawal policy, the paper was withdrawn in its entirety. It will not appear in Aging internal or any external indexes or archives.

WITHDRAWN: Exosomes derived from BDNF-expressing 293T attenuate ischemic retinal injury in vitro and in vivo

Figure 4. Integrins participated in the endocytosis of 293T-Exo by R28 cells. (A) Endocytosis was inhibited by pretreatment of RGD, but not by heparin. The nuclei were stained with DAPI (blue), the cytoskeleton was stained with tubulin (red), and 293T-Exo was stained with fluorescent-tag (green). Scale bar = 20 μm. (B) Efficacy of endocytosis of 293T-Exo by R28 cells was reversed due to increasing doses of RGD. (C) Efficacy of endocytosis of 293T-Exo by R28 cells was not affected by different doses of heparin. Data are presented as mean ± SD. *P < 0.05.