Research Paper Volume 12, Issue 23 pp 24242—24254

TNFAIP3 ameliorates the degeneration of inflammatory human nucleus pulposus cells by inhibiting mTOR signaling and promoting autophagy

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Figure 4. Knockdown of TNFAIP3 increases mTOR signaling in LPS-treated human NPCs. (A) The mTOR signaling was measured by Western blot in LPS-stimulated human NPCs at the phosphorylation level of mTOR at S2448. (B) Relative phosphorylation level of the mTOR. Data are represented by the mean ± standard deviation of 3 independent replicates. *** P<0.01, ** P<0.05, * P>0.05 by the Student’s t-test.