COVID-19 Research Paper Volume 12, Issue 20 pp 19911—19922
Short telomeres increase the risk of severe COVID-19
Figure 1. High proportion of COVID-19 patients with short telomeres and link with outcome. (A) As compared to the reference population (white bars), we found an enrichment of COVID-19 patients with short telomeres (black bars). (B) There is a statistically significant association between short telomeres (<P10) and COVID-19 (Chi-square test, P<0.0001). (C) There is a statistically significant association between short telomeres (<P10) and unfavorable outcome (admission in ICU and/or death) in COVID-19 hospitalized patients (Chi-square test, P=0.02). (D) Kaplan-Meyer curve showing the time to admission in ICU and/or death without in patients with TL <P10 or ≥P10.