Research Paper Volume 12, Issue 23 pp 23931—23944

Clinical and prognostic pan-cancer analysis of m6A RNA methylation regulators in four types of endocrine system tumors

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Figure 2. Identification of consensus clusters by m6A RNA methylation regulators in endocrine system tumors. (AC) Consensus clustering matrix for k = 2, and consensus clustering cumulative distribution function (CDF) for k = 2 to 9, and relative change in area under CDF curve for k = 2–9, and principal component analysis (PCA) of total RNA expression profiles in tumors data from the cancer genome atlas (TCGA) dataset; (D, E) Heatmaps, and Kaplan–Meier overall survival (OS) curve and clinicopathologic features of two clusters defined by consistent expression of the m6A regulatory genes (clusters1/2).