Single-cell expression profiles of <i>ACE2</i> and <i>TMPRSS2</i> reveals potential vertical transmission and fetus infection of SARS-CoV-2

Mengdie Lü; Li Qiu; Guangshuai Jia; Rongqun Guo; Qibin Leng

doi:doi:10.18632/aging.104015

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COVID-19 Research Paper Volume 12, Issue 20 pp 19880—19897

Single-cell expression profiles of ACE2 and TMPRSS2 reveals potential vertical transmission and fetus infection of SARS-CoV-2

Single-cell analysis of liver, pancreas and stomach. (A) t-distributed stochastic neighbor embedding (TSNE) plot showing sub-clusters of liver cells, (B) ACE2 and (C) TMPRSS2 expression in liver from the adult and fetal groups. (D) TSNE plot showing sub-clusters of stomach cells, (E) ACE2 and (F) TMPRSS2 expression in stomach from the adult and fetal groups. (G) TSNE plot showing sub-clusters of pancreas cells, (H) ACE2 and (I) TMPRSS2 expression in pancreas from the adult and fetal groups.