Research Paper Volume 12, Issue 19 pp 19701—19710

Voxel-based morphometry focusing on medial temporal lobe structures has a limited capability to detect amyloid β, an Alzheimer’s disease pathology

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(A) Histogram of VSRAD Z scores. VSRAD Z scores of PiB negative and positive patients were significantly different. However, histogram showed a vast overlap of scores between PiB positive and negative patients. (B) ROC analysis of VSRAD Z values.