Figure 1. USP10 mediates lipid uptake by macrophage. Cells were treated with Spautin-1 for 24 h or USP10 siRNA for 48 h. Dil-oxLDL was added for the additional 6 h. DAPI for cell nucleus. The images were taken by confocal microscopy (A, C) and by flow cytometry (E, G). The fluorescence intensity was performed using Image pro plus (B, D) and quantitative analysis was showed (F, H). *p<0.05, **p<0.01, ***p<0.001 versus each vehicle control. DM:DMSO.