Research Paper Volume 12, Issue 21 pp 21809—21836

Figure 2. PBRM1 mutations alter immune cell infiltration patterns in ccRCC samples. (A) Violin plots show different patterns of immune cell infiltration patterns in VHL^WT (90) and VHL^MUT (94) patients from the TCGA KIRC database. (B) Violin plots show different immune cell infiltration patterns in PBRM1^WT (97) and PBRM1^MUT (81) patients from the TCGA KIRC database. (C) Violin plots show stromal and immune purity scores from the ESTIMATE algorithm analyses for PBRM1^WT and PBRM1^MUT patients in the TCGA KIRC database. (D) Heatmap shows the mast cell infiltration status in PBRM1^MUT, VHL ^MUT, SETD2 ^MUT and BAP1 ^MUT ccRCC patients from the TCGA KIRC database.