Research Paper Volume 12, Issue 21 pp 21376—21390

The mechanism of submandibular gland dysfunction after menopause may be associated with the ferroptosis

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Figure 3. Mitochondria dysfunction. (A) Electron microscopy of submandibular gland in the CON and OVX groups. (B) Western blotting of antioxidant enzyme; SOD and catalase and control VDAC in the CON and OVX groups. (C) ROS generation in the CON and OVX groups. CON = control, OVX = ovariectomy, SOD = superoxide dismutase, CAT = catalase, VDAC = voltage-dependent anion channel.