Figure 3. SIF inhibited neuron loss after 4 weeks of treatment. HE staining was performed on the sections of the rat hippocampus. (A–D) Representative hippocampal photomicrographs of the four groups, 4x, scale bar = 50 μm; (E–H) Representative hippocampal photomicrographs of the four groups, 40x, scale bar = 20 μm. The arrows indicate positive signs of hippocampal neurons (shrunken or irregular shape and deeper staining).