Research Paper
Silencing of long non-coding RNA CASC15 enhances radiosensitivity of esophageal squamous cell carcinoma through microRNA-140-5p-dependent inhibition of MMP7
Figure 7. The regulatory mechanism of lncRNA CASC15/miR-140-5p/MMP7 axis involving in radiosensitivity of ESCC. LncRNA CASC15 up-regulates MMP7 expression in ESCC by binding to miR-140-5p, which promotes the proliferation and invasion of ESCC cells and further reduces the radiosensitivity of ESCC.