Research Paper Volume 12, Issue 20 pp 20254—20267

Development and validation of an immune and stromal prognostic signature in uveal melanoma to guide clinical therapy

class="figure-viewer-img"

Figure 3. Unsupervised clustering of immune and stromal cells for 80 patients in the UM cohort. (A, B) The low infiltration and high infiltration cells in immune and stromal group; (C) Kaplan-Meier curves for overall survival (OS) of UM patients show that immune infiltration patterns are significantly associated with overall survival (log-rank test, P = 0.004); (D) Kaplan-Meier curves for OS of UM patients show that stromal infiltration patterns are significantly associated with overall survival (log-rank test, P = 0.03). Hazard ratios (HRs) and 95% CIs are for high or low immune and stromal infiltration risk.