Research Paper Volume 12, Issue 20 pp 20163—20183

Down-regulated ciRS-7/up-regulated miR-7 axis aggravated cartilage degradation and autophagy defection by PI3K/AKT/mTOR activation mediated by IL-17A in osteoarthritis

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Effects of miR-7 related transfections on IL-17A levels determined by qRT-PCR (A) and ELISA (B). Data represent the mean ± SD (n = 3), * p < 0.05 and ** p < 0.01vs. IL-1β group.