Research Paper Volume 12, Issue 18 pp 18396—18414

Elevated serum IL-21 levels are associated with stable immune status in kidney transplant recipients and a mouse model of kidney transplantation

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Figure 8. Exogenous IL-21 induces B cell and T cell proliferation. Flow cytometry analysis to measure CD19+ B (A) and CD4+ T (B) lymphocytes in the peripheral blood and spleen of recipients and controls. Distribution of proportions of CD4+ T cells (C) and CD19+ B cells (D) of total lymphocytes on day 7 post-transplantation. Boxes and whiskers represent minimum to maximum of all the data. **P < 0.01 and ***P < 0.001 one-way ANOVA. ANOVA, analysis of variance; IL, interleukin.