Research Paper Volume 12, Issue 18 pp 18396—18414

Elevated serum IL-21 levels are associated with stable immune status in kidney transplant recipients and a mouse model of kidney transplantation

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Figure 1. Higher peripheral blood IL-21 levels in stable transplant recipients. Absolute concentration (pg/mL) of serum IL-2, IL-4, IL-6, IL-10, IL-12, IL-17, IL-21, IL-27, IFN-γ, and TNF-α (AJ) in recipients with (n = 36) and without (n = 30) active rejection after kidney transplantation. Red dash dot line represents the mean value. *P < 0.05 and **P < 0.01 compared with NR cohorts. IL, interleukin; IFN, interferon; NR, non-rejection; TNF, tumor necrosis factor.