Research Paper Volume 12, Issue 18 pp 18343—18362

Modeling mtDNA hypermethylation vicious circle mediating Aβ-induced endothelial damage memory in HCMEC/D3 cell

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Figure 2. The time course of relative change of mtDNA methylation, AKG, MMP, and cell vitality compared to the control group. The black line represent the control group level which is normalized to 100%. The blue line represent Aβ group level. The red line represent the damage memory group.