Figure 3. Age-related differentially expressed genes in the hypothalamus of rhesus macaque. (A–C) GO functional enrichment of age-related differentially expressed genes in the hypothalami of females (A) and males (C) (red: upregulated genes in middle age; blue: downregulated genes in middle age; each shows top 10 items). (B–D) Heatmaps of genes enriched in the items of (A, C). (E, F) Gene types of age-related differentially expressed genes in the hypothalami of females (E) and males (F).