Figure 3. Construction of the multi-feature fusion model. (A) Selection of tuning parameter lambda in the LASSO model used 10-fold cross-validation. The gray line in the figure is the partial likelihood estimate corresponding to the optimal value of lambda. The optimal lambda value of 2.653 was chosen. (B) LASSO coefficient profiles of the sixteen selected features. A vertical line was plotted at the optimal lambda value, which resulted in ten features with nonzero coefficients. (C) A nomogram was developed in the training data set with clinicopathological and MRI features. Calibration curves and ROC curves of the nomogram for the training set (D, G), validation set (E, H) and total population (F, I).