Research Paper Volume 12, Issue 15 pp 15566—15580

The association between KLF4 as a tumor suppressor and the prognosis of hepatocellular carcinoma after curative resection

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Figure 2. The prognostic analysis of KLF4 in HCC patients (n = 185) and subgroup analysis based on differentiation degree and BCLC stages. (A) According to KLF4 expression level in patients’ tissues with HCC, the curves described OS and RFS of patients, respectively. The OS in (B) differentiation I-II patients and (C) differentiation III-IV patients was analyzed by Kaplan- Meier method. The RFS in (D) differentiation I-II patients and (E) differentiation III-IV patients were analyzed by Kaplan- Meier method. Kaplan- Meier method was employed to analyze the OS of patients in (F) BCLC 0-A group and (G) BCLC B-C group. The RFS of patients in two subgroups (H and I) of the BCLC stage was analyzed through Kaplan- Meier analysis. P < 0.05 was considered statistically significant.