Research Paper Volume 12, Issue 18 pp 18019—18032
Long non-coding RNA AGAP2-AS1 increases the invasiveness of papillary thyroid cancer
Figure 1. AGAP2-AS1 expression is increased in PTC tissues and cells. (A) The fold change of AGAP2-AS1 expression between PTC tissues and paired non-cancerous tissues. (B) RT-PCR of AGAP2-AS1 levels in 110 pairs of PTC tissues and paired non-cancerous tissues. The Wilcoxon signed-rank test was used to analyze the differences between the two groups; data are presented as the median with a range. **P < 0.01. (C) RT-PRC of AGAP2-AS1 levels in TPC1, K1, BCPAP, and IHH4 PTC cells, and in a normal human thyroid follicular epithelial cell line (Nthy-ori 3-1). Data were analyzed using an independent samples t-test. *P < 0.05, **P < 0.01 vs. the Nthy-ori 3-1 group.