Research Paper Volume 12, Issue 14 pp 15011—15020
Circular RNA hsa_circ_0076690 acts as a prognostic biomarker in osteoporosis and regulates osteogenic differentiation of hBMSCs via sponging miR-152
Figure 3. (A) Predicted binding sites of miR-152 and RUNX2. (B) Dual-luciferase reporter assay showed RUNX2 was a target of miR-152. (C, D) The up-regulation of miR-152 and down-regulation of RUNX2 were validated by qRT-PCR in 57 pairs of OP and control samples.