Figure 8 — Prothrombotic effects of high uric acid in mice via activation of MEF2C-dependent NF-κB pathway by upregulating let-7c

Research Paper|Volume 12, Issue 18|pp. 17976–17989

Prothrombotic effects of high uric acid in mice via activation of MEF2C-dependent NF-κB pathway by upregulating let-7c

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Figure 8.The mechanism of HUA in thrombosis with involvement of let-7c and MEF2C. HUA repressed MEF2C to activate NF-κB pathway by upregulating let-7c, ultimately causing blood coagulation and thrombosis.