Research Paper Volume 12, Issue 14 pp 14718—14735

Demethoxycurcumin analogue DMC-BH inhibits orthotopic growth of glioma stem cells by targeting JNK/ERK signaling

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Figure 4. DMC-BH-induced apoptosis in GSCs is mediated by JNK/ERK signaling. (A) Phosphorylation protein levels in DMC-BH-treated GSCs analyzed by Proteome Profiler Human Phospho-Kinase Array. (B) Western analysis of phosphorylated levels of MAPK-related proteins p-ERK, p-JNK, p-c-Jun, and p-JunB in DMC-BH-treated GSCs.