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Research Paper Volume 12, Issue 14 pp 14434—14451

Characterization of aberrant pathways activation and immune microenviroment of BK virus associated nephropathy

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Figure 3. BKV was associated with increased plasma cell numbers and decreased naive CD4 T cell numbers. (A) The proportions of plasma cells in the PB (STA and BKV), TKB1 (STA and BKVN) and TKB2 (STA and BKVN) datasets. (B) The proportions of naive CD4 T cells in the PB (STA and BKV), TKB1 (STA and BKVN) and TKB2 (STA and BKVN) datasets. The thick line represents the median value. The bottom and top of the boxes indicate the 25th and 75th percentiles (interquartile range). The whiskers encompass 1.5 times the interquartile range. *, P< 0.05; **, P< 0.01; ***, P< 0.001; and ****, P<0.0001; Mann-Whitney U test.