Research Paper Volume 12, Issue 15 pp 15302—15313

Figure 3. Associations between serum metabolites and subclinical atherosclerosis. The point ranges represent odds ratios (95% confidence intervals) between each standard deviation increase in metabolites and high baPWV (left; baPWV >15.1 m/s) and increased IMT (right; IMT >0.80 mm), generated from logistic regression models. Model 1 (the dotted lines) was adjusted for age and sex; Model 2 (the solid lines) was additionally adjusted for baseline smoking, physical exercise, body mass index, systolic blood pressure, use of antihypertensive medications, diabetes mellitus, and hyperlipidemia. The significance threshold was set at ^*p<0.05, ^**p<0.01, and ^***p<0.001 after correcting for the false discovery rate. Abbreviations: baPWV, brachial-ankle pulse wave velocity; IMT, carotid intima-media thickness.