Research Paper Volume 12, Issue 13 pp 12812—12840

PHLPP2 is regulated by competing endogenous RNA network in pathogenesis of colon cancer

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Figure 7. Overexpressed LINC00402, LINC00461, and SFTA1P inhibit the proliferation and promote apoptosis of HT-29 cells. (A) Fluorescence image by EdU labeling (200 ×) evaluated cell proliferation when HT-29 cells were transfected with overexpressed LINC00402. (B) Fluorescence image by flow cytometry (200 ×) measured cell apoptosis when HT-29 cells were transfected with overexpressed LINC00402. (C) Fluorescence image by EdU labeling (200 ×) evaluated cell proliferation when HT-29 cells were transfected with overexpressed LINC00461. (D) Fluorescence image by flow cytometry (200 ×) assessed cell apoptosis when HT-29 cells were transfected with overexpressed LINC00461. (E) Fluorescence image by EdU labeling (200 ×) cell proliferation evaluated when HT-29 cells were transfected with overexpressed SFTA1P. (F) Fluorescence image by flow cytometry (200 ×) assessed cell apoptosis when HT-29 cells were transfected with overexpressed SFTA1P. * p < 0.05 vs. the NC-pcDNA group; # p < 0.05 vs. the NC-sh group; & p < 0.05 vs. the PHLPP2 group. Measurement data (proliferation rate and apoptosis rate) in this Figure were expressed as the mean ± standard deviation, and comparisons among multiple groups were conducted using One-Way ANOVA; the experiment was repeated three times independently.