Expression of Concern
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 12, Issue 13 pp 12812—12840
PHLPP2 is regulated by competing endogenous RNA network in pathogenesis of colon cancer
Figure 13. Regulatory mechanisms of LINC00402, LINC00461, SFTA1P, miR-141, miR-424 and PHLPP2 in colon cancer progression and metastasis. LINC00402 and LINC00461 competitively bind to miR-141, and SFTA1P competitively binds to miR-424 to regulate the transcription and translation of PHLPP2, thereby suppressing the proliferation, EMT process, migration, and invasion, preventing liver metastasis of colon cancer cells.