Figure 1. Immunohistochemistry of CCR1 in the bronchial mucosa of patients with COPD and control. (A) CCR1 expression (brown staining) from a patient with COPD. (B) CCR1 expression (brown staining) from a control. (C) Representative CCR1 expression (brown staining) from a patient with COPD. (D) Representative CCR1 expression (brown staining) from a control. (E) Quantification of the histochemistry results, expressed as integral optical density of brown staining in the different views of patients with COPD and controls. The results are presented as mean ± SEM. Original magnification ×200 or ×400. ** p <0.01.