Figure 3. The effect of uric acid on extending life span depends on its activation of transcription factor SKN-1. (A) Life span analysis of the skn-1(zu67) mutant exposed to 2 mM uric acid and that of the untreated control. (B) Life span analysis of wild-type animals exposed to skn-1 RNAi treated with 2 mM uric acid and that of the untreated control. The P value was calculated by the log-rank test, and the life span values of the replicated tests are listed in