Figure 1. Cross-sectional associations of Mitochondrial DNA Copy Number (mtDNAcn) with DNA Methylation Age (DNAm-Age), DNAm-PhenoAge, DNAm-GrimAge, and Telomere Length. The effect estimates (β) and corresponding 95% confidence intervals were estimated with linear mixed models adjusted for chronological age, smoking, alcohol use, BMI, hypertension status, CHD status, diabetes status, blood cell type composition, and follow up time.