Figure 6. ISG20 promoted ccRCC cell proliferation in vitro. (A-B) The si-ISG20 could effectively inhibit the expression of ISG20. (C–E) CCK-8 assays were used to detect the effect of ISG20 knockdown on the proliferation of ccRCC cell lines (786O, A498, and OSRC-2). (F–H) Clone formation assays were used to detect the effect of the ISG20 knockdown on the clone formation ability. ccRCC: clear cell renal cell carcinoma; CCK-8: cell counting kit - 8. Data are represented as mean ± SD. ***, P < 0.001; **, P < 0.01; *, P < 0.05.