Figure 1. Plasma UCHL1 levels according to Hoehn-Yahr stage. Values are mean ± SEM. Plasma UCHL1 levels were significantly higher in PD patients at H&Y stage >2.5 (n=35), compared to controls (n=49) and mild PD patients at H&Y stage ≤2.0 (n=207), controlled for age, gender and Bonferroni method. Abbreviation: HC = Health Control; PD = Parkinson’s disease; HY = Hoehn-Yahr stage.