Research Paper Volume 11, Issue 24 pp 12295—12314

ERK1 indicates good prognosis and inhibits breast cancer progression by suppressing YAP1 signaling

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Figure 7. ERK1 and ERK2 expression were associated with distinct prognostic features of breast cancer. (AC) Kaplan-Meier Plotter analysis indicated that high expression of ERK1 was associated with prolonged OS, recurrence and DMFS in patients with breast cancer. (D) Kaplan-Meier Plotter analysis indicated that high expression of ERK1 was associated with prolonged OS in patients receiving endocrine therapy. (EG) Kaplan-Meier Plotter analysis showed that the high expression of ERK2 was associated with poor OS, recurrence and DMFS in patients with breast cancer. (H) Kaplan-Meier Plotter analysis indicated that high expression of ERK2 was not associated with OS in patients receiving endocrine therapy.