Figure 7 — Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes

Research Paper|Volume 11, Issue 23|pp. 11520–11540

Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes

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Figure 7.BMP4 may suppress hepatic steatosis and alleviate the development and progression of NAFLD by inhibiting mTORC1 signaling. BMP4 decrease the expression of S6K, p-S6K and SREBF1, while increase the expression of LIPIN1.