Melatonin modulates IL-1β-induced extracellular matrix remodeling in human nucleus pulposus cells and attenuates rat intervertebral disc degeneration and inflammation

Yan Zhang; Fan He; Zhi Chen; Qihang Su; Meijun Yan; Qiang Zhang; Jun Tan; Lie Qian; Yingchao Han

doi:doi:10.18632/aging.102472

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Research Paper Volume 11, Issue 22 pp 10499—10512

Melatonin modulates IL-1β-induced extracellular matrix remodeling in human nucleus pulposus cells and attenuates rat intervertebral disc degeneration and inflammation

Figure 7. Immunohistochemical staining of each group 8w after puncture. (A) Representative images of IL-1β staining. (B) Representative images of IL-6 staining. (C) Representative images of TNF-α staining.