Research Paper Volume 11, Issue 22 pp 10031—10051

DNA methylation profile is a quantitative measure of biological aging in children

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Figure 2. Schematic of the prediction model. A flow diagram of the child-specific methylation-based age prediction model. The green boxes represent the input data, the red diamonds represent the analysis methods and the blue ovals represent the prediction results. AAD: age acceleration difference; AMAR: apparent methylation aging rate; SIS: sure independence screening.