Research Paper Volume 11, Issue 20 pp 9147—9166

Dysfunctional interactions between the default mode network and the dorsal attention network in subtypes of amnestic mild cognitive impairment

Figure 1. Altered functional connectivity within the DMN among the four groups. (A) Spatial distribution of the DMN (FWE correction). (B) Regions showing hypo- and hyperconnectivity within the DMN in the AD group; (C) Regions showing hypo- and hyperconnectivity within the DMN in the aMCI-m group; (D) Regions showing hypo- and hyperconnectivity within the DMN in the aMCI-s group. Abbreviations: DMN: default mode network; RSC: retrosplenial cortex; V1: primary visual cortex; MOG: middle occipital gyrus; PCC: posterior cingulate cortex; PCL: paracentral lobule; AG: angular gyrus; AD: Alzheimer's disease; aMCI-s: single-domain of amnestic mild cognitive impairment; aMCI-m: multiple-domain of amnestic mild cognitive impairment; NC: normal controls.