Figure 7. The effect of COL6A6 on the growth and metastasis of xenograft tumor by mediating PI3K-Akt pathway. (A and B) The tumor size was obtained from nude mice; C and E: The tumor weight was measured; (D and F) The tumor volume curve of nude mice was analyzed. **P<0.01, ***P<0.001, compared with control group; ##P<0.01, ###P<0.001, compared with COL6A6 group.