Research Paper Volume 11, Issue 16 pp 6469—6489

Identification and validation of four hub genes involved in the plaque deterioration of atherosclerosis

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Figure 1. Dataset selection flow chart and analysis processes. (A) In total, 136 datasets from Gene Expression Omnibus (GEO) and 94 datasets from ArrayExpress were evaluated. Finally, 4 datasets for mRNAs were selected for inclusion in the comprehensive analysis. (B) The present study consisted of 5 steps, and the results of the analysis were finally validated on clinical samples.