Figure 2. Correlation of age acceleration measures. The three epigenetic measures of age acceleration were all positively correlated with each other. Phenotypic age acceleration had the lowest correlation with the other two (r = 0.51, p <2.2e-16 with intrinsic age acceleration; r = 0.52, p <2.2e-16 with extrinsic age acceleration). Intrinsic age acceleration and extrinsic age acceleration had the highest correlation (r = 0.62, p < 2.2e-16).