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Research Paper Volume 11, Issue 14 pp 4990—5007

Long noncoding RNA FALEC inhibits proliferation and metastasis of tongue squamous cell carcinoma by epigenetically silencing ECM1 through EZH2

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Figure 6. FALEC suppress TSCC progression by downregulating ECM1. SCC-9 and CAL-27 cells transfected with pcDNA/pcDNA-FALEC/pcDNA-ECM1 and cells transfected with pcDNA-FALEC followed by transfection with pcDNA-ECM1. After transfection, the cells were analyzed by CCK-8 assays (A), EdU assays (B), Colony formation assays (C) and transwell assays (D). Data are shown as means ± SD. *p < 0.05, **p < 0.01, ***p < 0.001.