Expression of Concern
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This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 11, Issue 10 pp 3348—3361
circFADS2 protects LPS-treated chondrocytes from apoptosis acting as an interceptor of miR-498/mTOR cross-talking
Figure 6. miR-498 inhibitor reversed the effects of circFADS2 on LPS-treated chondrocytes. LPS-treated chondrocytes were co-transfected with si-circFADS2 and miR-498 inhibitor/miR-NC inhibitor. (A) qPCR analysis was performed to confirm the miR-498 levels in each group. (B, C) The mRNA and protein expression of the indicated proteins was determined by qPCR and WB. (D) The IL-6 level in cells was examined by ELISA. Results were normalized to GAPDH expression. *P < 0.05, **P < 0.01 vs. LPS group; # P < 0.05, ## P < 0.01, ### P < 0.001 vs. LPS+circFADSi+miR-NCi group.