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Figure 8
Figure 8.DRm217 and PP2 attenuated but ouabain strengthened AngII effect on increasing of collagen I, malondialdehyde and IL-1β in HK-2 cell. mRNA level of collagen I (A), contents of malondialdehyde contents (B), and contents of IL-1β (C) in different-treated cells. AngII increased the expression of collagen I, malondialdehyde and IL-1β, whereas, DRm217 and PP2 decreased but ouabian increased the expression of collagen I, malondialdehyde and IL-1β in AngII-treated cells. n=4. Means±SEM; * p<0.05, **p<0.01, vs control group (Con); # p<0.05, ## p<0.01, vs AngII group.