Research Paper Volume 11, Issue 2 pp 673—696

Figure 3. Identification of a prognostic signature based on differential features between IDH^WT and IDH^MUT LGGs. (A) The expression pattern of 16 radiomic features along with the elevation of the risk score. The corresponding survival data and IDH status are listed. (B) In 158 LGGs cohort, the IDH^MUT patients survived longer than the IDH^WT patients (P = 0.0045, HR = 0.4024, 95%CI:0.16–0.70). (C) The risk score divided the LGGs into two groups with distinct outcomes (P = 0.0017, HR = 0.3207, 95%CI:0.19–0.68). (D) IDH^MUT LGGs with a low risk score showed a favorable prognosis compared with the IDH^WT patients (P = 0.0483, HR = 0.4232, 95%, CI:0.17–0.99). (E) Further, the overall survival time of the IDH^MUT patients with a high risk score was not significantly different from that of the IDH^WT (P = 0.199).