Figure 2 — Geniposide-mediated protection against amyloid deposition and behavioral impairment correlates with downregulation of mTOR signaling and enhanced autophagy in a mouse model of Alzheimer's disease

Research Paper|Volume 11, Issue 2|pp. 536–548

Geniposide-mediated protection against amyloid deposition and behavioral impairment correlates with downregulation of mTOR signaling and enhanced autophagy in a mouse model of Alzheimer's disease

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Figure 2.Geniposide improves NOR scores in APP/PS1 mice(A) Schematic diagram of the NOR test. (B) NOR test results. The DI of APP/PS1 mice was significantly decreased compared to WT, and was improved by geniposide treatment. Data are mean ± SEM (n = 13–15). ^***p < 0.001 vs. WT; ^#p < 0.05 vs. APP/PS1. (one-way ANOVA, Tukey's Multiple Comparison Test). WT: wild-type mice. GP: geniposide.