Figure 1.Metformin increases the adult and total mean lifespan in the male silkworm. (A) Adult stage (n=27), (B) mean total lifespan (n=30), and (C) maximum lifespan (n=3) of unmated female silkworms administered metformin (Treatment) or deionized water (Control). (D) Adult stage (n=24), (E) mean total lifespan (n=54) and (F) maximum lifespan of unmated male silkworms administered metformin (Treatment) of deionized water (Control). Bars depict the mean + SEM, *P < 0.05, **P < 0.01, ***P < 0.001.
