Research Paper Volume 10, Issue 10 pp 2973—2990

Figure 3. Hazards ratio models show high correlation with each other and are strongly associated with average level of physical activity and the largest variance in physiological measurements (PC₁). (A) Scatter plots of estimated mortality hazard ratio (log-scale) vs PC₁ scores and log-hazard ratio estimated by “LogMort” model trained on NHANES survival follow-up data shows high correlation (see text). (B) Different models for hazard ratio of mortality and morbidity show high correlation between each other and the PC₁ "biological age" in NHANES samples. Models for mortality and morbidity were built using Cox proportional hazards method based on either NHANES or UKB death follow-up data and UKB follow-up on diagnosis. All values were adjusted by age and gender and thus represent the corresponding Biological Age Acceleration (BAA) values.