Research Paper Volume 10, Issue 7 pp 1776—1788

Human methionine synthase A2756G polymorphism increases susceptibility to prostate cancer

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Figure 5. In-silico analysis of MTR expression. (A) The relative expression of MTR in PCa tissue and paracancerous tissue (Normal) using TCGA database. TPM (Transcripts Per Kilobase Million) stands for the expression of MTR in each tissue. MTR expression in PCa tissue was lower than that in normal tissue (data from 502 PCa and 158 normal samples, P < 0.05). The correlation between MTR expression and overall survival time (B) or disease free survival time (C) of prostate cancer patients (P > 0.05).