Research Paper Volume 9, Issue 11 pp 2302—2315

Selenium preserves keratinocyte stemness and delays senescence by maintaining epidermal adhesion

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Figure 4. Keratinocyte relative adhesion to type IV collagen or laminin 332 during replicative senescence. Keratinocytes from 2 donors over subculture passages with or without SeNa supplementation and seeding at each passage on pre-coated wells with 10 µg/ml type IV collagen (on the left) or with 2 µg/ml laminin 332 (on the right). Results are the mean of n=3 measurements ± SD normalized to the mean of adhesion obtain from poly-D-lysine coated plates. *p<0.025, **p<0.005, ***p<0.0002.